Trends in TB epidemiology -- Natural History of TB and latent TB -- The BCG vaccine -- Contact tracing and screening new entrants – science, rationale and progress -- Pulmonary, Pleural and Mediastinal TB – clinical aspects and diagnosis -- Lymph Node/ Abdominal/ Renal /Pericardial TB – clinical aspects, diagnosis and managing paradoxical reactions -- Radiology of TB -- Routine Laboratory Diagnostic Techniques -- TB and HIV issues -- Spinal and Bone TB -- CNS and Meningeal TB – management -- Molecular tools – current and future applications in the reference laboratory -- Therapeutic Drug Monitoring -- MDR TB Management -- The interferon gamma release assays – science and rationale -- TB in renal disease -- Anti-TNF, immunosuppression approaches in TB -- Occupational Health Screening -- Infection Control -- Supporting the Hard to Reach -- Incident Management and ‘Mass screening’ -- Paediatric TB Issues -- TB treatment and complications -- A Global TB Overview.

This book is targeted at ensuring frontline clinical staff including seniors, trainees and specialist nurses can easily reference the optimum investigation and management of potential TB cases. This will mirror the annual London Advanced TB course which aims to equip all of the team delivering care to have a working knowledge of the entire spectrum of the real life aspects of TB management ranging from investigation of active TB to latent screening in pre biologic therapy. It includes an update of MDR TB management and also the approaches needed to ensure the entire medico-social spectrum of TB care is addressed.