Part I. History -- Chapter 1. History of Cardiac Pacing -- Chapter 2. History of Defibrillation -- Chapter 3. History of Cardiac Mapping -- Chapter 4. History of Optical Mapping -- Part II. Theory of Electric Stimulation and Defibrillation -- Chapter 5. The Bidomain Theory of Pacing -- Chapter 6. Bidomain Theory of Defibrillation -- Chapter 7. The Generalized Activating Function -- Part III. Electrode Mapping and Defibrillation -- Chapter 8. Extracellular Mapping of Arrhythmia -- Chapter 9. Critical Points and the Upper Limit of Vulnerability for Defibrillation -- Chapter 10. Inverse Potential Methods of Cardiac Mapping -- Chapter 11. Monophasic Action Potential -- Part IV. Optical Mapping of Stimulation and Defibrillation -- Chapter 12. Mechanisms of Isolated Cell Stimulation -- Chapter 13. The Role of Microscopic Tissue Structure in Defibrillation -- Chapter 14. Virtual Electrode Theory of Pacing -- Chapter 15. The Virtual Electrode Hypothesis of Defibrillation -- Chapter 16. Simulataneous Optical andElectrical Recording -- Chapter 17. Advanced 3D Optical Mapping -- Chapter 18. Electromechanical Optical Mapping Methods -- Part V. Methodology -- Chapter 19. The Bidomain Model of Cardiac Tissue: From Microscale to Macroscale -- Chapter 20. Newer Models of Cardiac Tissue -- Chapter 21. The Role of Electroporation -- Chapter 22. RF Versus Cryo Ablation -- Chapter 23. Electroanatomical Mapping -- Part VI. Implications for Implantable Devices -- Chapter 24. Lessons for the Clinical Implant -- Chapter 25. Resonance and Feedback Strategies for Low-Voltage Defibrillation -- Chapter 26. Pacing Control of Local Cardiac Dynamics -- Chapter 27. Advanced Methods for Assessing the Stability and Control of Alternans -- Chapter 28. The Future of Implantable Defibrillator -- Chapter 29. Lessons Learnt from Implantable Cardioverter -Defibrillators Recordings -- Part VII. Novel Arrhythmia Therapies -- Chapter 30. Optogenetic Control of Arrhythmias -- Chapter 31. Subcutaneous Defibrillation -- Chapter 32. Future High-Resolution Mapping -- Chapter 33. Conformal Electronics Therapy for Defibrillation -- Chapter 34. Multistage Defibrillation Therapy -- Chapter 35. Implantable Cardioverter Defibrillator to Cardiac Implantable Electronic Device -- Chapter 36. Leadless Pacing -- Chapter 37. Direct His-bundle Pacing -- Chapter 38. Artificial Intelligence/Machine Learning/Deep Learning -- Chapter 39. Wearable Devices for Ambulatory Cardiac and Respiratory Monitoring.

The updated and expanded second edition of this book presents a contemporary review of the basic science, engineering technology, and clinical practice of cardiac bioelectric therapy. It covers the rapidly expanding technological development of pacemakers and defibrillators as well as ablative therapy, electrophysiological mapping, and other clinical diagnostic and therapeutic breakthroughs. The book highlights many different aspects of bioelectric therapy, including history, biophysical and computational concepts, basic electrophysiology studies, engineering technology advances, and clinical perspectives. In this revised edition, leading clinical and basic electrophysiologists share their perspectives on the science behind the mechanisms of cardiac arrhythmias; breakthrough technologies for scientific and clinical investigation of heart rhythm disorders; theoretical conceptualization of arrhythmias and treatment using state-of-the-art computational approaches; and novel approaches to treatment of cardiac arrhythmias using implantable devices, percutaneous ablation therapies, machine learning, and other approaches. The Second Edition of Cardiac Bioelectric Therapy is an essential resource for physicians, residents, fellows, and graduate students in clinical cardiac electrophysiology, cardiology, and cardiac surgery as well as researchers, professionals, and students in biomedical, mechanical, and electrical engineering. .